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    Using two separate drugs to shed pounds can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err on the side of caution and let the FDA do its job and demand some research be done so that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say everything to keep people on the medications.

    Researchers discovered that participants taking this drug to get a year, dropped a few pounds within one month and have kept the extra weight off through the 56 weeks of the study. Contrave can be a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of many active ingredient, that might make them more effective and safer.

    Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that by right now there are not any long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

    Seizures really are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise blood pressure and pulse rate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not be used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    "This may be the first drug I'm mindful of that targets the two appetite and reward centres inside brain," he was quoted saying.

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